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Ohashi N., Harada S., Mizuguchi T., Irah … 続きを読む

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Maruta Y., Kuwata T., Tanaka K., Alam M., Ramirez-Valdez K-P., Egami Y., Yoshiaki Suwa Y., Morioka H., Matsushita S. Cross-neutralization activity of single-chain variable fragment (scFv) derived from anti-V3 monoclonal antibodies mediated by post-attachment binding. Jpn. J. Infect. Dis.,in press, 2016

Maruta Y., Kuwata T., Tanaka K., Alam M. … 続きを読む

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Mizuguchi T., Harada S., Miura T., Ohashi N., Narumi T, Mori H.; Irahara Y; Yamada Y.; Nomura W., Matsushita S., Yoshimura K, Tamamura H. Minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 26:397-400, 2016.

Mizuguchi T., Harada S., Miura T., Ohash … 続きを読む

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Boonchawalit, S., Harada, S, Shirai, N., Gatanaga, H., Oka, S., Matsushita, S., and Yoshimura, K. Impact of maraviroc-resistant mutation M434I in the C4 region of HIV-1 gp120 on sensitivity to antibody-mediated neutralization. Jpn. J. Infec.t Dis., in press, 2016.

Boonchawalit, S., Harada, S, Shirai, N., … 続きを読む

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Kuwata, T., Enomoto, I., Baba, M. and Matsushita S. Incompatible natures of HIV-1 envelope in resistance to the CCR5 antagonist cenicriviroc and neutralizing antibodies.Antimicrobial Agents and Chemotherapy (AAC)  Accepted manuscript posted online 2 November 2015, doi: 10.1128/AAC.02285-15

Kuwata, T., Enomoto, I., Baba, M. and Ma … 続きを読む

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Ramirez, K., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., Matsushita, S. Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains. Virology, 475, 187-203, 2015.doi:10.1016/j.virol.2014.11.011

Ramirez, K., Kuwata, T., Maruta, Y., Tan … 続きを読む

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Matsushita, S., Yoshimura, K., Ramirez, k., Pisupati, J., Murakami, T., the KD-1002 Study Group. Passive transfer of neutralizing mAb KD-247 reduces plasma viral load in patients chronically infected with HIV-1. AIDS, 29(4), 453-462, 2015. doi: 10.1097/QAD.0000000000000570

Matsushita, S., Yoshimura, K., Ramirez, … 続きを読む

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Kirby, K.A., Ong Y.T., Hachiya, A., Laughlin, T.G., Chiang, L.A., Pan, Y., Moran, J.L., Marchand, B., Singh, K., Gallazzi, F., Quinn, T.P., Yoshimura, K., Murakami, T., Matsushita, S., Sarafianos, S.G.. Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247. The FASEB Journal, 29(1), 70-80, 2015.

Kirby, K.A., Ong Y.T., Hachiya, A., Laug … 続きを読む

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Yoshimura, K., Harada, S., Boonchawalit, S., Kawanami, Y., and Matsushita, S. Impact of maraviroc-resistant and low-CCR5- adapted mutations induced by in vitro passage on sensitivity to anti-envelope neutralizing antibodies. Journal of General Virology, 95, 1816-1826, 2014.

Yoshimura, K., Harada, S., Boonchawalit, … 続きを読む

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Otsuki, H., Hishiki, T., Miura, T., Hashimoto, C., Narumi, T., Tamamura, H., Yoshimura, K., Matsushita, S., and Igarashi, T. Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic. J. Gen. Virol. 94: 2710-2716, 2013.

Otsuki, H., Hishiki, T., Miura, T., Hash … 続きを読む

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Hashimoto, C., Narumi, T., Otsuki, H., Hirota, Y., Arai, H., Yoshimura, K., Harada, S., Ohashi, N., Nomura, W., Miura, T., Igarashi, T., Matsushita, S. and Tamamura, H. A CD4 mimic as an HIV entry inhibitor: Pharmacokinetics. Bioorg. Med. Chem. 21: 7884?7889 , 2013.

Hashimoto, C., Narumi, T., Otsuki, H., H … 続きを読む

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The Mind Exchange Working Group (Antinori A, Arendt G, Grant I, Matsushita S, et al.) Assessment, Diagnosis, and Treatment of HIV-Associated Neurocognitive Disorder: A Consensus Report of the Mind Exchange Program. Clin Infect Dis. 56(7):1004 -1017, 2013

The Mind Exchange Working Group (Antinor … 続きを読む

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Harada S, Yoshimura K, Yamaguchi A, Yusa K, Matsushita S. Impact of antiretroviral pressure on selection of primary HIV-1 envelope sequences in vitro. J. Gen. Virol. 94:933-943, 2013.

Harada S, Yoshimura K, Yamaguchi A, Yusa … 続きを読む

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Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov KI, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Conformational Epitope Consisting of the V3 and V4 Loops as a Target for Potent and Broad Neutralization of Simian Immunodeficiency Viruses. J. Virol. 87:5424-5346, 2013.

Kuwata T, Takaki K, Yoshimura K, Enomoto … 続きを読む

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Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H.: CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents. Bioorganic & Medicinal Chemistry. 21:2518-2526, 2013 .

Narumi T, Arai H, Yoshimura K, Harada S, … 続きを読む

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Kuwata T, Takaki K, Enomoto I, Kazuhisa Y, and Matsushita S. Increased infectivity in human cells and resistance to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail. Frontiers in Microbiology/Virology. 4:1-7, 2013.

Kuwata T, Takaki K, Enomoto I, Kazuhisa … 続きを読む

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Nishijima T, Takano M, Ishisaka M, Komatsu H, Gatanaga H, Kikuchi Y, Endo T, Horiba M, Kaneda S, Uchiumi H, Koibuchi T, Naito T, Yoshida M, Tachikawa N, Ueda M, Yokomaku Y, Fujii T, Higasa, S., Takada, K., Yamamoto, M, Matsushita S, Tateyama M, Tanabe Y, Mitsuya H, Oka S, on behalf of the Epzicom-Truvada study team: Abacavir/Lamivudine versus Tenofovir/Emtricitabine with Atazanavir/Ritonavir for Treatment-naive Japanese Patients with HIV-1 Infection: A Randomized Multicenter Trial. Internal Medicine. 52: 735-744, 2013.

Nishijima T, Takano M, Ishisaka M, Komat … 続きを読む

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Yokoyama M, Naganawa S, Yoshimura K, Matsushita S, Sato H. Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop. PLoS ONE. 7(5): e37530, 2012.

Yokoyama M, Naganawa S, Yoshimura K, Mat … 続きを読む

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Ong YT, Kirby KA, Hachiya A, Chiang LA, Marchand B, Yoshimura K, Murakami T, Singh K, Matsushita S, Sarafianos SG. Preparation of biological active single-chain variable antibody fragments that target the HIV-1 gp120 v3 loop. Cellular and Molecular Biology. 58: 71-79, 2012

Ong YT, Kirby KA, Hachiya A, Chiang LA, … 続きを読む

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Honda M, Ishisaka M, Ishizuka N, Kimura S, Oka S and behalf of Japanese Anti-HIV-1 QD Therapy Study Group. Open-Label Randomized Multicenter Selection Studyof Once Daily Antiretroviral Treatment Regimen Comparing Ritonavir-Boosted Atazanavir to Efavirenz with Fixed-Dose Abacavir and Lamivudine. Internal Medicine. 50: 699-705,2011.

Honda M, Ishisaka M, Ishizuka N, Kimura … 続きを読む

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Narumi, T., Arai, H.,Yoshimura, K.,Harada, S., Nomura, W., Matsushita, S., Tamamura. H. Small molecular CD4 mimics as HIV entry inhibitors. Bioorg Med Chem , 19: 6735-6742 ,2011.

Narumi, T., Arai, H.,Yoshimura, K.,Harad … 続きを読む

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4. Narumi, T., Ochiai, C., Yoshimura, K., Harada, S., Tanaka,T., Nomura,W., Arai, H., Ozaki, T., Ohashi, N., Matsushita, S., Tamamura, H. :CD4mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters. 5853- 5858, 2010.

Narumi, T., Ochiai, C., Yoshimura, K., H … 続きを読む

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Yoshimura, K., Harada, S., Shibata, J., Hatada, M., Yamada, Y., Ochiai, C., Tamamura, H., Matsushita, S. :Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds. J. Virol. 84:7558-7568, 2010.

Yoshimura, K., Harada, S., Shibata, J., … 続きを読む

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Hatada, M., Yoshimura, K., Harada, S., Kawanami, Y., Shibata, J., Matsushita S. HIV-1 evasion of a neutralizing anti-V3 antibody involves acquisition of a potential glycosylation site in V2. J. Gen. Virol. 91: 1335-1345, 2010. 

Hatada, M., Yoshimura, K., Harada, S., K … 続きを読む

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Yamada, Y., Ochiai, C., Yoshimura, K., Tanaka, T., Ohashi, N., Narumi, T., Nomura, W., Harada, S., Matsushita, S., Tamamura, H. CD4 mimics targeting the mechanism of HIV entry. Bioorganic & Medicinal Chemistry Letters 20: 354–358, 2010.

Yamada, Y., Ochiai, C., Yoshimura, K., T … 続きを読む

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Ryo, A., Tsurutani, N., Ohba, K., Kimura, R., Komano, J., Nishi, M., Soeda, H., Hattori,S., , Perrem, K., Yamamoto, M., Chiba, J., Mimaya, J., Yoshimura, K., Matsushita, S., Honda, M., Yoshimura, A., Sawasaki, T., Aoki, I., Morikawa, Y., and Yamamoto, N. SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag. Proc Natl Acad Sci U S A. 105:294-299, 2008.

Ryo, A., Tsurutani, N., Ohba, K., Kimura … 続きを読む

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Ikeda T, Ohsugi T, Kimura T, Matsushita S., Maeda Y, Harada S, Koito A. The anti-retroviral potency of APOBEC1 deaminase from small animal species. Nuleic Acids Research, 36(21): 6859-6871, 2008.

Ikeda T, Ohsugi T, Kimura T, Matsushita … 続きを読む

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Ikeda T, Shibata J, Yoshimura K,Koito A, Matsushita S. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective HAART.J. Infect. Dis.195:716-725, 2007 .

Ikeda T, Shibata J, Yoshimura K,Koito A, … 続きを読む

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Shibata J, Yoshimura K, Honda A.,Koito A, Murakami T. Matsushita S. Impact of V2 mutations for escape from a potent neutralizing anti-V3 monoclonal antibody during in vitro selection of a primary HIV-1 isolate. J. Virol. 81:3757-3768,2007

Shibata J, Yoshimura K, Honda A.,Koito A … 続きを読む

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Gatanaga H, Hayashida T, Tsuchiya K, Yoshino M, Kuwahara T, Tsukada H, Fujimoto K, Sato I, Ueda M, Horiba M, Hamaguchi M, Yamamoto M, Takata N, Kimura A, Koike T, Gejyo F, Matsushita S, Shirasaka T, Kimura S, Oka S.: Successful efavirenz dose reduction in HIV-1-infeccted individuals with cytochrome P450 2B6*6 and *26. Clinical Infectious Diseases., 45: 1230-1237, 2007.

Gatanaga H, Hayashida T, Tsuchiya K, Yos … 続きを読む

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Nakayama E.E., Carpentier W, Costagliola D., Shioda T., Iwamoto A., Debre P, Yoshimura K, Autran B, Matsushita S, Theodorou I. Wild type and H43Y variant of human TRIM5α show similar anti-human immunodeficiency virus type 1 activity both in vivo and in vitro. Immunogenetics 59:511-515, 2007.

Nakayama E.E., Carpentier W, Costagliola … 続きを読む

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Eda Y, Takizawa M, Murakami T., Maeda H., Kimachi K., YonemuraH, Koyanagi S, Shiosaki K, Higuchi H, Makizumi K, Nakashima T ,Osatomi K., Tokiyoshi S, Matsushita S, Yamamoto N. Honda M. Sequential immunization with V3 peptides from primary HIV-1 produces cross-neutralizing antibodies against primary isolates with matching narrow neutralization sequence motif.J. Virol. 80:5552-5562,2006.

Eda Y, Takizawa M, Murakami T., Maeda H. … 続きを読む

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Eda Y, Murakami T, Ami Y, Nakasone T, Takizawa M, Someya K, Kaizu M, Izumi Y., Yoshino, N., Matsusita, S.,Higuchi, H., Matsui, H., Shinohara, K., Takeuchi, H., Koyanagi, S., Yamamoto, N. and Honda M. Anti-V3 humanized antibody KD-247 effectively suppresses ex vivo generation of human immunodeficiency virus type 1 and affordssterile protection of monkeys against a heterologous simian/human immunodeficiency virus infection. J. Virol. 80:5563-5570, 2006

Eda Y, Murakami T, Ami Y, Nakasone T, Ta … 続きを読む

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Davis DA, Brown CA, Singer KE., Wang V, Kaufman J, Stahl SJ, Wingfield P, Maeda K, Harada S, Yoshimura K, Kosalaraksa, P, Mitsuya H, Yarchoan R Antiviral Res. 72:89-99, 2006

Davis DA, Brown CA, Singer KE., Wang V, … 続きを読む

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Yoshimura K, Shibata J, Kimura T, Honda A, Maeda Y, Koito A, Murakami T, Mitsuya H, Matsushita S. Resistance profile of a neutralizing anti-HIV monoclonal antibody, KD-247, that shows favorable synergism with anti-CCR5 inhibitors. AIDS .20:2065-2073, 2006.

Yoshimura K, Shibata J, Kimura T, Honda … 続きを読む

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Matsushita S., Yoshimura, K., Kimura T., Kamihira, A., Takano, M., Eto, K., Shirasaka, T., Mitsuya, H., Oka, S.: Spontaneous recovery of hemoglobin and neutrophil levels in Japanese patients on a long-term CombivirR containing regimen. J.Clin.Virol. 33:188-193, 2005

Matsushita S., Yoshimura, K., Kimura T., … 続きを読む

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Sakaguchi N, Kimura T., Matsushita S, Fujimura S, Shibata J, Araki M, Sakamoto T, Minoda S, and Kuwahara K.Generation of high-affinity antibody against T cell- dependent antigen in ganp gene- transgenic mouse. J. Immunol. 174:4485-4494,2005.

Sakaguchi N, Kimura T., Matsushita S, Fu … 続きを読む

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Matsushita S, Takahama S., Shibata J., Kimura T., Shiozaki K., Eda Y., Koito A., Murakami T, and Yoshimura K. Ex vivo neutralization of HIV-1 quasispecies by a broadly reactive humanized monoclonal antibody KD247. Human Antibodies. 14:80-88, 2005

Matsushita S, Takahama S., Shibata J., K … 続きを読む

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Tamiya S., Mardy S., Kavlick M.F., Yoshimura K, Mistuya H.  Amino acid insertions near Gag cleavage sites restore the otherwise compromised replication of human immunodeficiency virus type 1 variants resistant to protease inhibitors. J. Virol. 78:12030-12040, 2004.

Tamiya S., Mardy S., Kavlick M.F., Yoshi … 続きを読む

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Koito A, Shigekane H, Matsushita S. Ability of small animal cells to support post integration phase of human immunodeficiency virus type 1 replication. Virology, 305:181-191, 2003.

Koito A, Shigekane H, Matsushita S. Abil … 続きを読む

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Koito A,Kameyama Y, Cheng-Mayer C, Matsushita S. Susceptibility of mink (Mustera vision)-derived cells to replication by human immunodeficiency virus type-1. J Virol, 77:5109-511, 2003

Koito A,Kameyama Y, Cheng-Mayer C, Matsu … 続きを読む

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Yoshimura K, Ido E., Akiyama H, Kimura T, Aoki M, Suzuki H., Mitsuya H, Hayami M, Matsushita S. The impact of highly active antiretroviral therapy by the oral route on the CD8 subset in monkeys infected chronically with SHIV89.6P. J Virol Methods. 112:121-128, 2003.

Yoshimura K, Ido E., Akiyama H, Kimura T … 続きを読む

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Gatanaga, H., Suzuki, Y., Tsang, H., Yoshimura, K., Kavlick, M.F., Nagashima, K., Gorelick, R.J., Mardy, S., Tang, C., Summers, M.F., Mitsuya, H.: Amino acid substitutions in gag protein at non-cleavage sited are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors. J. Biol. Chem. 277:5952-5961, 2002.

Gatanaga, H., Suzuki, Y., Tsang, H., Yos … 続きを読む

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Matsushita, S. Kimura, T. Advance in treatment strategy and immune reconstruction against HIV-1 infection. Microbiol. Immunol., 46(4):231-239, 2002. [PDF]

Matsushita, S. Kimura, T. Advance in tre … 続きを読む

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Wang FX, Kimura T, Nishihara K., Yoshimura K.,Koito A, Matsushit S. Emergence of autologous neutralization-resistant variants from pre existing quasispecies during viral-rebound of human immunodeficency virus type-1 infected patients under treatment of highly active anti retroviral therapy (HAART) . J Infect Dis, 185:608-617, 2002.

Wang FX, Kimura T, Nishihara K., Yoshimu … 続きを読む

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Kimura T, Yoshimura K., Nishihara K., Maeda Y, Matsumi S,Koito A, Matsushita S. Reconstitution of spontaneous neutralizing antibody response against autologous HIV-1 in chronically infected patients during highly active antiretroviral therapy. J. Infect. Dis., 185:53-60,  2002.

Kimura T, Yoshimura K., Nishihara K., Ma … 続きを読む

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Yoshimura K, Kato R , Kavlick MF, Nguyen A, Maroun V, Maeda K., Hussain K., Ghosh A., Erickson J, Mitsuya H. A Potent Protease Inhibitor (PI) UIC-94003 Interacting with Main Chains of HIV Protease Active Site Amino Acids and the Development of a Novel Mutation A28S in the Protease of UIC-94003-Resistant HIV. J Virol, 76:1349-1357, 2002.

Yoshimura K, Kato R , Kavlick MF, Nguyen … 続きを読む

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Maeda, K., Yoshimura, K., Shibayama, S., Habashita, H., Tada, H., Sagawa, K., Miyakawa, T., Aoki, M., Fukushima, D., and Mitsuya, H. Novel Low Molecular Weight Spirodiketopiperazine Derivatives Potently Inhibit R5 HIV-1 Infection through Their Antagonistic Effects on CCR5. J. Biol. Chem. 276:35194-35200, 2001.

Maeda, K., Yoshimura, K., Shibayama, S., … 続きを読む

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Ikegawa M, Matsumoto K, Herrmann S, Iwamoto A, Nakamura T, Matsushita S, Nakamura T, Honjo T, Tashiro K: Elevated plasma SDF-1 protein level in the progression of HIV-1 infection/AIDS. AIDS Res Hum Retrov. 17(7):587-595, 2001

Ikegawa M, Matsumoto K, Herrmann S, Iwam … 続きを読む

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Sei, S., Yang, Q. E., O’Neill, D., Yoshimura, K., Nagashima, K., and Mitsuya, H. Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain. J. Virol. 74:4621-33, 2000.

Sei, S., Yang, Q. E., O’Neill, D., … 続きを読む

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Falloon, J., Piscitelli, S., Vogel, S., Sadler, B., Mitsuya, H., Kavlick, M. F., Yoshimura, K., Rogers, M., LaFon, S., Manion, D. J., Lane, H. C., and Masur, H. Combination therapy with amprenavir, abacavir, and efavirenz in human immunodeficiency virus (HIV)-infected patients failing a protease- inhibitor regimen: pharmacokinetic drug interactions and antiviral activity. Clin. Infect. Dis. 30:313-308, 2000.

Falloon, J., Piscitelli, S., Vogel, S., … 続きを読む

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Ohrui, H., Kohgo, S., Kitano, K., Sakata, S., Kodama, E., Yoshimura, K., Matsuoka, M., Shigeta, S., and Mitsuya, H. Syntheses of 4′-C-Ethynyl-beta-D-arabino- and 4′-C-Ethynyl-2’deoxy- beta-D-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity. J. Med. Chem. 43:4516-4525, 2000.

Ohrui, H., Kohgo, S., Kitano, K., Sakata … 続きを読む

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Murakami T, Nakajima N, Nakamura T, Hara A., Uyama E., Mita S, Matsushita S, Uchino M. Parkinsonian symptoms as an initial manifestation in a Japanese patient with acquired immunodeficiency syndrome and toxoplasma infection. Internal Medicine 39, 1111-1114, 2000.

Murakami T, Nakajima N, Nakamura T, Hara … 続きを読む

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Tugarinov V, Zvi A, Levy R, Hayek Y, Matsushita S, Anglister J. NMR structure of an anti gp-120 antibody complex with a V3-peptide reveals a surface important for co-receptro binding. Structure 8, 385-395. 2000.

Tugarinov V, Zvi A, Levy R, Hayek Y, Mat … 続きを読む

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Matsushita S. Current status and future issues in the treatment of HIV infection. Int. J. Hematol. 72(1):20-27, 2000

Matsushita S. Current status and future … 続きを読む

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Maeda Y, Foda M, Matsushita S, Harada S. Involvement of both V2 and V3 region of CCR5-tropic human immunodeficiency virus type-1 envelope for reduced sensitivity to macrophage inflammatory protein α J Virol 74(4), 1787-1793, 2000

Maeda Y, Foda M, Matsushita S, Harada S. … 続きを読む

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Yoshimura K, Kato R, Yusa K, Kavlick MF, Maroun V, Nguyen A, Mimoto T, Ueno T, Shintani M, Falloon J, Masur H, Hayashi H, Erickson J, Mitsuya H. JE-2147: a dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1. Proc Natl Acad Sci USA. 96:8675-80., 1999.

Yoshimura K, Kato R, Yusa K, Kavlick MF, … 続きを読む

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Yoshimura K,Feldman R, Kodama E, Kavlick MF, Qiu YL, Zemlicka J, Mitsuya H. In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues. Antimicrob Agents Chemother. 43:2479-83, 1999.

Yoshimura K,Feldman R, Kodama E, Kavlick … 続きを読む

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Matsumi S, Maeda Y, Kimura T, Matsushita S. Effect of the Th1 and Th2 stimulatory cytokines, IL-12 and IL-4, on HIV-1 specific CTL activity. 12th World AIDS Conference, Appendix 5: 45-50, 1998.

Matsumi S, Maeda Y, Kimura T, Matsushita … 続きを読む

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Wang J, Harada K., Matsushita S, Matsumi S, Zhang Y, Shioda T, Nagai Y, Matsushima K. IL-4 and a glucocorticoid up-regulate CXCR4 expression on human CD4+ T lymphocytes and enhance HIV-1 replication. J. Leukocyte Biology., 64:642-649,1998.

Wang J, Harada K., Matsushita S, Matsumi … 続きを読む

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Shoji S, Kazuchika K, Ogata A, Yamataka K., Mukai K., Uda A., Harano S, Matsushita S, Misumi S. An allisteric drug, o’o’-bismyristoyl thiamine disulfide, suppresses HIV-1 replication through prevention of nuclear translocation of both HIV-1 tat and NF-ΚB. Biochem. Biophys. Res. Commun., 249, 745-753, 1998.

Shoji S, Kazuchika K, Ogata A, Yamataka … 続きを読む

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Hakata Y, Umemoto T., Matsushita S, Shida H. Involvement of human CRM1 (Exportin 1) in the export and multimerization of the Rex protein of the human T-cell leukemia virus type 1. J. Virol. 72: 6602-6607, 1998.

Hakata Y, Umemoto T., Matsushita S, Shid … 続きを読む

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