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新センター発足

2019年4月1日より分野名が「ヒトレトロウイルス学共同研究センター・臨床レトロウイル学分野」になりました。
Publication

Ohashi N., Harada S., Mizuguchi T., Irahara Y., Yamada Y., Kotani M., Nomura W., Matsushita S., Yoshimura K., Tamamura H...
Publication

Maruta Y., Kuwata T., Tanaka K., Alam M., Ramirez-Valdez K-P., Egami Y., Yoshiaki Suwa Y., Morioka H., Matsushita S. Cross-neutralization activity of single-chain variable fragment (scFv) derived from anti-V3 monoclonal antibodies mediated by post-attachment binding. Jpn. J. Infect. Dis.,69(5):395-404, 2016

Maruta Y., Kuwata T., Tanaka K., Alam M., Ramirez-Valdez K-P., Egami Y., Yoshiaki Suwa Y., Morioka H., Matsushita S. Cro...
Publication

Mizuguchi T., Harada S., Miura T., Ohashi N., Narumi T, Mori H.; Irahara Y; Yamada Y.; Nomura W., Matsushita S., Yoshimura K, Tamamura H. Minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 26:397-400, 2016.

Mizuguchi T., Harada S., Miura T., Ohashi N., Narumi T, Mori H.; Irahara Y; Yamada Y.; Nomura W., Matsushita S., Yoshimu...
Publication

Boonchawalit, S., Harada, S, Shirai, N., Gatanaga, H., Oka, S., Matsushita, S., and Yoshimura, K. Impact of maraviroc-resistant mutation M434I in the C4 region of HIV-1 gp120 on sensitivity to antibody-mediated neutralization. Jpn. J. Infec.t Dis., in press, 2016.

Boonchawalit, S., Harada, S, Shirai, N., Gatanaga, H., Oka, S., Matsushita, S., and Yoshimura, K. Impact of maraviroc-re...
Publication

Kuwata, T., Enomoto, I., Baba, M. and Matsushita S. Incompatible natures of HIV-1 envelope in resistance to the CCR5 antagonist cenicriviroc and neutralizing antibodies.Antimicrobial Agents and Chemotherapy (AAC)  Accepted manuscript posted online 2 November 2015, doi: 10.1128/AAC.02285-15

Kuwata, T., Enomoto, I., Baba, M. and Matsushita S. Incompatible natures of HIV-1 envelope in resistance to the CCR5 ant...
Domestic Conference

Muntasir, A., Kuwata, T., Ramirez, K., Maruta, Y., Tanaka, K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushita, S. Effect of gp41 mutations on the sensitivity to neutralizing antibodies against HIV. 第29回日本エイズ学会学術集会・総会. 2015年11月30日-12月1日,東京.

Muntasir, A., Kuwata, T., Ramirez, K., Maruta, Y., Tanaka, K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushi...
Domestic Conference

平田 泉、桑田岳夫、丸田泰広、田中和樹、Muntasir, A.、松下修三 ファージ・ライブラリーを用いた抗 V3単クローン抗体のエピトープ解析. 第29回日本エイズ学会学術集会・総会. 2015年11月30日-12月1日,東京.

平田 泉、桑田岳夫、丸田泰広、田中和樹、Muntasir, A.、松下修三 ファージ・ライブラリーを用いた抗 V3単クローン抗体のエピトープ解析. 第29回日本エイズ学会学術集会・総会. 2015年11月30日-12月1日,東京.
Domestic Conference

Kuwata, T., Shimizu, M., Matsushita, S. Impact of gp41 mutations on resistance to B404, a broad neutralizing antibody reactive against a conformational epitope of SIV gp120. 第63回日本ウイルス学会学術集会. 2015年11月22日-24日,福岡市.

Kuwata, T., Shimizu,  M., Matsushita, S.   Impact of gp41 mutations on resistance to B404, a broad neutralizing antibody...
Domestic Conference

Tanaka, K. Kuwata T., Maruta, Y., Muntasir, A., Kawanami, Y.,Matsushita, S. Enhanced neutralization by small antibody fragments targeting CD4i (CD4-induced) epitope on HIV-1 envelope glycoprotein. 第63回日本ウイルス学会学術集会. 2015年11月22日-24日,福岡市.

Tanaka, K. Kuwata T., Maruta, Y., Muntasir, A., Kawanami, Y.,Matsushita, S.  Enhanced neutralization by small antibody f...
Publication

Ramirez, K., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., Matsushita, S. Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains. Virology, 475, 187-203, 2015.doi:10.1016/j.virol.2014.11.011

Ramirez, K., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., Matsushita, S. Complementary and synergistic a...
Publication

Matsushita, S., Yoshimura, K., Ramirez, k., Pisupati, J., Murakami, T., the KD-1002 Study Group. Passive transfer of neutralizing mAb KD-247 reduces plasma viral load in patients chronically infected with HIV-1. AIDS, 29(4), 453-462, 2015. doi: 10.1097/QAD.0000000000000570

Matsushita, S., Yoshimura, K., Ramirez, k., Pisupati, J., Murakami, T., the KD-1002 Study Group. Passive transfer of neu...
International Conference

Stanoeva, K., Fukuda, A., Kawanami, Y, Kuwata, T., Satou, Y., Matsushita, S.: Levels of integrated proviral HIV-1 DNA load in Japanese patients on long-term ART. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Stanoeva, K., Fukuda, A., Kawanami, Y, Kuwata, T., Satou, Y., Matsushita, S.: Levels of integrated proviral HIV-1 DNA lo...
International Conference

Maruta, Y., Kuwata, T., Tanaka, K., Ramirez, K., Alam, M., Egami, Y., Suwa, Y., Morioka, H., Matsushita, S.: Post-attachment neutralization by single-chain variable fragments targeting the V3 loop of HIV-1 envelope. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Maruta, Y., Kuwata, T., Tanaka, K., Ramirez, K., Alam, M., Egami, Y., Suwa, Y., Morioka, H., Matsushita, S.: Post-attach...
International Conference

Alam, M., Kuwata, T., Maruta, Y., Ramirez K., Tanaka, K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushita, S.: HIV-1 gp41 mutations against fusion inhibitor C34 showed enhanced sensitivity to neutralizing antibodies. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Alam, M., Kuwata, T., Maruta, Y., Ramirez K., Tanaka, K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushita, S...
International Conference

Tanaka, K., Kuwata, T., Maruta, Y., Ramirez K., Alam, M., Kawanami, Y., Matsushita S.: Enhanced neutralization of HIV-1 primary isolates by the small antibody fragments targeting CD4-induced (CD4i) epitope. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Tanaka, K., Kuwata, T., Maruta, Y., Ramirez K., Alam, M., Kawanami, Y., Matsushita S.: Enhanced neutralization of HIV-1 ...
International Conference

Alves, G., Kuwata T., Tanaka Y., Ariumi, Y., Maruta, Y., Tanaka, K., Alam, M., Stanoeva, K., Hirata, I., Matsushita, S.: Constitutive expression of anti-HIV-1 scFv intrabodies transduced by an HIV-1-based Lentivirus vector. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Alves, G., Kuwata T., Tanaka Y., Ariumi, Y., Maruta, Y., Tanaka, K., Alam, M., Stanoeva, K., Hirata, I., Matsushita, S.:...
International Conference

Hirata, I., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Matsushita, S.: Epitope analysis of anti-V3 monoclonal antibodies using phage display library. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Hirata, I., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Matsushita, S.: Epitope analysis of anti-V3 monoclonal antibod...
International Conference

Kuwata, T., Shimizu, M., Matsushita, S. Impact of gp41 mutations for escape from a broad neutralizing antibody against SIV. 16th Kumamoto AIDS Seminar. October 7-9, 2015. Kumamoto.

Kuwata, T., Shimizu, M., Matsushita, S. Impact of gp41 mutations for escape from a broad neutralizing antibody against S...
未分類

IAS 2015 Vancouver,Canada(2015/7/19-22)にて、博士課程3年の田中和樹さんが「IAS Towards an HIV Cure Scholarship Programme」を獲得しました。

IAS 2015  Vancouver,Canada(2015/7/19-22)にて、博士課程3年の田中和樹さんが「IAS  Towards an HIV Cure Scholarship Programme」を獲得しました。  詳し...
International Conference

Tanaka, K., Kuwata, T., Maruta, Y., Ramirez, K., Alam, M., Egami, Ikumi Y., Enomoto, I., Kawanami, Y., Matsushita. S. Potent and broad neutralizing activity of small antibody fragments targeting CD4i (CD4-induced) epitope. The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) the Vancouver 19-22 July 2015. Vancouver, Canada.

Tanaka, K., Kuwata, T., Maruta, Y., Ramirez, K., Alam, M., Egami, Ikumi Y., Enomoto, I., Kawanami, Y., Matsushita. S. Po...
Domestic Conference

桑田岳夫、田中和樹、丸田泰広、松下修三. Neutralization of HIV-1 by single chain antibody fragments (scFv) against gp120. 白馬シンポジウム in 米子. 2015年6 月19 日-20 日, 米子市.

桑田岳夫、田中和樹、丸田泰広、松下修三. Neutralization of HIV-1 by single chain antibody fragments (scFv) against gp120. 白馬シンポジウム in 米子. 20...
Domestic Conference

田中和樹、桑田岳夫、丸田泰広、松下修三.  Potent and broad neutralizing activity of small antibody fragments targeting CD4i (CD4-induced) epitope. 白馬シンポジウム in 米子. 2015年6 月19 日-20 日(土).米子市.

田中和樹、桑田岳夫、丸田泰広、松下修三.  Potent and broad neutralizing activity of small antibody fragments targeting CD4i (CD4-induced) ep...
International Conference

Muntasir, A., Kuwata, T., Ramirez, K., Maruta, Y., Tanaka K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushita, S. Enhanced Neutralization of HIV-1 with Fusion Inhibitor Resistant Mutations. The annual Conference on Retroviruses and Opportunistic Infections (CROI 2015). February 23-26, 2015. Seattle, Washington, USA

Muntasir, A., Kuwata, T., Ramirez, K., Maruta, Y., Tanaka K., Shimura, K., Oishi, S., Fujii, N., Matsuoka, M., Matsushit...
International Conference

Matsushita, S., Ramirez, K.P., Maruta, Y., Tanaka, K., Muntasir, A., Kuwata, T., Pisupait, J., Murakami, T., Yoshimura, K. Therapeutic application of neutralizing antibodies based on the recent data on complementary and synergistic activities against a wide range of HIV-1 strains. the 17th International Conference on Emerging Infectious Diseases (EID) Emerging Infectious Diseases Meeting Jan. 26-27, 2015. Taipei, Taiwan

Matsushita, S., Ramirez, K.P., Maruta, Y., Tanaka, K., Muntasir, A., Kuwata, T., Pisupait, J., Murakami, T., Yoshimura, ...
Publication

Kirby, K.A., Ong Y.T., Hachiya, A., Laughlin, T.G., Chiang, L.A., Pan, Y., Moran, J.L., Marchand, B., Singh, K., Gallazzi, F., Quinn, T.P., Yoshimura, K., Murakami, T., Matsushita, S., Sarafianos, S.G.. Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247. The FASEB Journal, 29(1), 70-80, 2015.

Kirby, K.A., Ong Y.T., Hachiya, A., Laughlin, T.G., Chiang, L.A., Pan, Y., Moran, J.L., Marchand, B., Singh, K., Gallazz...
International Conference

Maruta, Y ., Kuwata, T., Tanaka, K ., Nakahara, Y ., Ramirez, K., Muntasir, A., Egami, Y., Hirata, I., Suwa, Y ., Morioka, H., Matsushita, S. Post-attachment Neutralization by Single-chain Variable Fragment (scFv) from an Anti-V3 Monoclonal Antibody with Cross-reactivity. Korea-Japan Joint Seminar on HIV/AIDS. January 10, 2015. Kumamoto.

Maruta, Y ., Kuwata, T., Tanaka, K ., Nakahara, Y ., Ramirez, K., Muntasir, A., Egami, Y., Hirata, I., Suwa, Y ., Moriok...
Domestic Conference

Ramirez, K.P., Kuwata, T., Maruta, Y, Tanaka K., Muntasir, A., Yoshimura, K., Matsushita, S. Complementary effect of anti-V3, CD4bs and CD4i antibodies accounts for cross-neutralizing and non-neutralizing activities against HIV-1. 第28回日本エイズ学会学術集会・総会. 2014年12月3日-5日, 大阪.

Ramirez, K.P., Kuwata, T., Maruta, Y, Tanaka K., Muntasir, A., Yoshimura, K., Matsushita, S. Complementary effect of ant...
Domestic Conference

江上由華、丸田泰広、田中和樹、Muntasir A., Ramirez K., 桑田岳夫、松下修三.  V3エピトープへの交叉反応性をもつ中和抗体の遺伝子組み換えによる小型化の試み.  第28回日本エイズ学会学術集会・総会. 2014年12月3日-5日, 大阪.

江上由華、丸田泰広、田中和樹、Muntasir A., Ramirez K., 桑田岳夫、松下修三.  V3エピトープへの交叉反応性をもつ中和抗体の遺伝子組み換えによる小型化の試み.  第28回日本エイズ学会学術集会・総会. 2014年12...
Domestic Conference

桑田岳夫、松下修三. 強力な抗SIV中和抗体B404からの逃避メカニズムの解析. 第28回日本エイズ学会学術集会・総会. 2014年12月3日-5日, 大阪.

桑田岳夫、松下修三. 強力な抗SIV中和抗体B404からの逃避メカニズムの解析. 第28回日本エイズ学会学術集会・総会. 2014年12月3日-5日, 大阪.
International Conference

Kuwata, T., Yoshimura, K., Wu, F., Ourmanov, I., Hirsch, V.M., Yokoyama, M., Sato H., and Matsushita, S.  Mutations in gp41 is Critical to Escape from B404, a Broad Neutralizing Antibody Against SIV, Which Recognizes a V3/V4 Conformational Epitope. 32nd Annual Symposium on Nonhuman Primate Models for AIDS. November 11 – 14, 2014. Portland, Oregon, USA.

Kuwata, T., Yoshimura, K., Wu, F., Ourmanov, I., Hirsch, V.M., Yokoyama, M., Sato H., and Matsushita, S.  Mutations in g...
International Conference

Maruta, Y., Kuwata, T., Tanaka K., Nakahara,Y., Ramirez, K., Alam, M., Egami, Y., Hirata I., Suwa, Y., Morioka, H., Matsushita, S. Mechanism of post-attachment neutralization of single-chain variable fragment (scFv) from anti-V3 monoclonal antibody against HIV-1.  HIV R4P 2014 .  October 28-31,2014. Cape Town, South Africa. 

Maruta, Y., Kuwata, T., Tanaka K., Nakahara,Y., Ramirez, K., Alam, M., Egami, Y., Hirata I., Suwa, Y., Morioka, H., Mats...
Publication

Yoshimura, K., Harada, S., Boonchawalit, S., Kawanami, Y., and Matsushita, S. Impact of maraviroc-resistant and low-CCR5- adapted mutations induced by in vitro passage on sensitivity to anti-envelope neutralizing antibodies. Journal of General Virology, 95, 1816-1826, 2014.

Yoshimura, K., Harada, S., Boonchawalit, S., Kawanami, Y., and Matsushita, S. Impact of maraviroc-resistant and low-CCR5...
International Conference

Matsushita, S., Ramirez, K.P., Maruta, Y., Tanaka, K., Muntasir, A., Kuwata, T., Pisupait, J., Murakami, T., Yoshimura, K. Therapeutic application of neutralizing antibodies based on the recent data on complementary and synergistic activities against a wide range of HIV-1 strains. 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Matsushita, S., Ramirez, K.P., Maruta, Y., Tanaka, K., Muntasir, A., Kuwata, T., Pisupait, J., Murakami, T., Yoshimura, ...
International Conference

Kuwata, T., Enomoto, I., Baba, M., Matsushita, S. Acquisition of resistance to the CCR5 antagonist cenicriviroc renders HIV-1 sensitive to neutralizing antibodies. 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Kuwata, T., Enomoto, I., Baba, M., Matsushita, S. Acquisition of resistance to the CCR5 antagonist cenicriviroc renders ...
International Conference

Ramirez, K.P., Kuwata, T., Maruta, Y, Tanaka K., Muntasir, A., Yoshimura, K., Matsushita, S. Evaluation of complementarity and synergy of conventional anti-HIV-1 antibodies derived from a single individual, 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Ramirez, K.P., Kuwata, T., Maruta, Y, Tanaka K., Muntasir, A., Yoshimura, K., Matsushita, S. Evaluation of complementari...
International Conference

Muntasir, A., Kuwata, T., Ramirez, K., Enomoto, I., Maruta, Y., Tanaka K., Rahman K., Nakahara,Y., Egami, Y., Kawanami, Y., Murayama, H., Shimura, K., Matsuoka, M., Matsushita, S. Mutations in gp41 that confer resistance to fusion inhibitors enhance the neutralization sensitivity to antibodies against both gp41 and gp120. 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Muntasir, A., Kuwata, T., Ramirez, K., Enomoto, I., Maruta, Y., Tanaka K., Rahman K., Nakahara,Y., Egami, Y., Kawanami, ...
International Conference

Maruta, Y., Kuwata, T., Tanaka K., Nakahara,Y., Ramirez, K., Alam, M., Egami, Y., Hirata I., Suwa, Y., Morioka, H., Matsushita, S. Mechanism of post-attachment neutralization of single-chain variable fragment (scFv) from anti-V3 monoclonal antibody against HIV-1. 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Maruta, Y., Kuwata, T., Tanaka K., Nakahara,Y., Ramirez, K., Alam, M., Egami, Y., Hirata I., Suwa, Y., Morioka, H., Mats...
International Conference

Tanaka K., Kuwata, T., Maruta, Y., Ramirez, K., Muntasir, A., Egami, Y., Enomoto, I., Kawanami, Y., Matsushita, S. Construction of neutralizing antibody fragment against V3 with a broad cross-reactivity. 15th Kumamoto AIDS Seminar. October 1-3, 2014. Kumamoto.

Tanaka K., Kuwata, T., Maruta, Y., Ramirez, K., Muntasir, A., Egami, Y., Enomoto, I., Kawanami, Y., Matsushita, S. Const...
International Conference

Boonchawalit, S., Harasda, S., Matsushita, S., Yoshimura, K.: Impact of Maraviroc (MCV)-resistant mutations in C1 and C4 regions of gp120 on sensitivity to antibody-mediated neutralization. 20th International AIDS Conference. Melbourne, Australia. July 20-25,2014.

Boonchawalit, S., Harasda, S., Matsushita, S., Yoshimura, K.: Impact of Maraviroc (MCV)-resistant mutations in C1 and C4...
Domestic Conference

桑田岳夫:SIVサル・モデルを用いた中和抗体の解析. 第17回 日本レトロウイルス研究会 夏期セミナー.2014 7.3-5(7/3発表)静岡県熱海市.

桑田岳夫:SIVサル・モデルを用いた中和抗体の解析. 第17回 日本レトロウイルス研究会 夏期セミナー.2014 7.3-5(7/3発表)静岡県熱海市.
Domestic Conference

桑田岳夫、馬場昌範、松下修三:CCR5阻害薬Cenicrivirocへの耐性と中和抗体への抵抗性は両立しない. 白馬シンポジウムin熊本. 2014.6.13-14. 熊本市.

桑田岳夫、馬場昌範、松下修三:CCR5阻害薬Cenicrivirocへの耐性と中和抗体への抵抗性は両立しない. 白馬シンポジウムin熊本. 2014.6.13-14. 熊本市.
Domestic Conference

桑田岳夫、馬場昌範、松下修三:HIV-1 のCCR5 阻害薬への耐性と中和抗体への抵抗性は両立しない第24回抗ウイルス療法研究会総会. 2014.5.7-9.(5/7発表)  山梨県富士吉田市.

桑田岳夫、馬場昌範、松下修三:HIV-1 のCCR5 阻害薬への耐性と中和抗体への抵抗性は両立しない第24回抗ウイルス療法研究会総会. 2014.5.7-9.(5/7発表)  山梨県富士吉田市.
Domestic Conference

松下修三, 大類 諭, Post F, Winston J, Hendry B, Gazzard B, Molina J, Liu HC, Piontkowsky D, Cheng AK, Rhee MS, Szwarcberg J. EVG/COBI/FTC/TDF 第III 相臨床試験における腎機能に関連する安全性の評価(投与96 週時点)-アジア人についての層別集計結果を含む-. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日, 熊本.

松下修三, 大類 諭, Post F, Winston J, Hendry B, Gazzard B, Molina J, Liu HC, Piontkowsky D, Cheng AK, Rhee MS, Szwarcberg J. EV...
Domestic Conference

桑田岳夫. シンポジウム6-中和抗体と抗CCR5 阻害薬(Env). 第27回日本エイズ学会学術集会・総会.  2013年11月20日-22日, 熊本.

桑田岳夫. シンポジウム6-中和抗体と抗CCR5 阻害薬(Env). 第27回日本エイズ学会学術集会・総会.  2013年11月20日-22日, 熊本.
Domestic Conference

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Matsushita S. Combination of anti-V3 antibodies as a possible strategy for controllingtransmitted/founder virus. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日, 熊本.

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Matsushita S. Combinati...
Domestic Conference

丸田泰広, 桑田岳夫, 田中和樹, Ramirez K, Alam M, 江上由華, 中原悠介, 諏訪喜昭, 森岡弘志, 松下修三. 抗V3 抗体の小型化によるCD4 結合後のHIV-1 中和活性の増進. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日, 熊本.

丸田泰広, 桑田岳夫, 田中和樹, Ramirez K, Alam M, 江上由華, 中原悠介, 諏訪喜昭, 森岡弘志, 松下修三. 抗V3 抗体の小型化によるCD4 結合後のHIV-1 中和活性の増進. 第27回日本エイズ学会学術集会・総...
Domestic Conference

Alam M, Kuwata T, Ramirez K, Enomoto I, Maruta Y, Tanaka K, Rahman K, Egami Y, Kawanami Y, Murayama H, Shimura K, Matsuoka M, Matsushita S. Enfuvirtide resistant mutation N43Dis associated with the enhancedneutralization by 10E8, a broadlyneutralizing antibody against gp41 MPER. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日, 熊本.

Alam M, Kuwata T, Ramirez K, Enomoto I, Maruta Y, Tanaka K, Rahman K, Egami Y, Kawanami Y, Murayama H, Shimura K, Matsuo...
Domestic Conference

田中和樹, 桑田岳夫, 丸田泰広, Ramirez K, 松下修三. gp120のCD4-induced epitope に結合する中和抗体の小型化とその特性の検討. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日, 熊本.

田中和樹, 桑田岳夫, 丸田泰広, Ramirez K, 松下修三. gp120のCD4-induced epitope に結合する中和抗体の小型化とその特性の検討. 第27回日本エイズ学会学術集会・総会. 2013年11月20日-22日,...
International Conference

Alam M, Kuwata T, Ramirez K, Enomoto I, Maruta Y, Tanaka K, Rahman K, Egami Y, Kawanami Y, Murayama H, Shimura K, Matsuoka M, Matsushita S. Effects of Enfuvirtide resistant mutations on the sensitivity to neutralizing antibodies. 14th Kumamoto AIDS Seminar. 29-31 October 2013, Kumamoto.

Alam M, Kuwata T, Ramirez K, Enomoto I, Maruta Y, Tanaka K, Rahman K, Egami Y, Kawanami Y, Murayama H, Shimura K, Matsuo...
International Conference

Maruta Y, Kuwata T, Tanaka K, Nakahara Y, Ramirez K, Alam M, Egami Y, Suwa Y, Morioka H, Matsushita S. Post-attachment neutralization as a mechanism of efficient activities of scFv from anti-V3 monoclonal antibody. 14th Kumamoto AIDS Seminar. 29-31 October 2013, Kumamoto.

Maruta Y, Kuwata T, Tanaka K, Nakahara Y, Ramirez K, Alam M, Egami Y, Suwa Y, Morioka H, Matsushita S. Post-attachment n...
International Conference

Tanaka K, Kuwata T, Maruta Y, Ramirez K, Kawanami Y, Enomoto I, Matsushita S. Miniaturization of antibodies against CD4-induced epitope on gp120. 14th Kumamoto AIDS Seminar. 29-31 October 2013, Kumamoto.

Tanaka K, Kuwata T, Maruta Y, Ramirez K, Kawanami Y, Enomoto I, Matsushita S. Miniaturization of antibodies against CD4-...
International Conference

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Rahman K, Egami Y, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Matsushita S. Can antibodies contribute to controlling infection with transmitted/founder virus? 14th Kumamoto AIDS Seminar.  29-31 October 2013, Kumamoto.

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Rahman K, Egami Y, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Mats...
International Conference

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov I, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Identification of the Env region responsible for the resistance to B404, a potent neutralizing antibody against SIV. 14th Kumamoto AIDS Seminar. 29-31 October 2013, Kumamoto.

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov I, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Identificatio...
Publication

Otsuki, H., Hishiki, T., Miura, T., Hashimoto, C., Narumi, T., Tamamura, H., Yoshimura, K., Matsushita, S., and Igarashi, T. Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic. J. Gen. Virol. 94: 2710-2716, 2013.

Otsuki, H., Hishiki, T., Miura, T., Hashimoto, C., Narumi, T., Tamamura, H., Yoshimura, K., Matsushita, S., and Igarashi...
Publication

Hashimoto, C., Narumi, T., Otsuki, H., Hirota, Y., Arai, H., Yoshimura, K., Harada, S., Ohashi, N., Nomura, W., Miura, T., Igarashi, T., Matsushita, S. and Tamamura, H. A CD4 mimic as an HIV entry inhibitor: Pharmacokinetics. Bioorg. Med. Chem. 21: 7884?7889 , 2013.

Hashimoto, C., Narumi, T., Otsuki, H., Hirota, Y., Arai, H., Yoshimura, K., Harada, S., Ohashi, N., Nomura, W., Miura, T...
International Conference

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Rahman K, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Matsushita S. Improving the brodality and potency of neutralizing anti-HIV-1 antibodies with a CD4 mimetic compound. AIDS Vaccine 2013. 7-10 October 2013. Barcelona, Spain.

Ramirez K, Kuwata T, Maruta Y, Tanaka K, Alam M, Rahman K, Kawanami Y, Enomoto I, Tamamura H, Yoshimura K, Matsushita S....
International Conference

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov I, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Analysis of Env regions important for binding and resistance to B404, a potent neutralizing antibody against SIV. AIDS Vaccine 2013. 7-10 October 2013. Barcelona, Spain.

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov I, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Analysis of E...
Publication

The Mind Exchange Working Group (Antinori A, Arendt G, Grant I, Matsushita S, et al.) Assessment, Diagnosis, and Treatment of HIV-Associated Neurocognitive Disorder: A Consensus Report of the Mind Exchange Program. Clin Infect Dis. 56(7):1004 -1017, 2013

The Mind Exchange Working Group (Antinori A, Arendt G, Grant I, Matsushita S, et al.) Assessment, Diagnosis, and Treatme...
Publication

Harada S, Yoshimura K, Yamaguchi A, Yusa K, Matsushita S. Impact of antiretroviral pressure on selection of primary HIV-1 envelope sequences in vitro. J. Gen. Virol. 94:933-943, 2013.

Harada S, Yoshimura K, Yamaguchi A, Yusa K, Matsushita S. Impact of antiretroviral pressure on selection of primary HIV-...
Publication

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov KI, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Conformational Epitope Consisting of the V3 and V4 Loops as a Target for Potent and Broad Neutralization of Simian Immunodeficiency Viruses. J. Virol. 87:5424-5346, 2013.

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov KI, Hirsch VM, Yokoyama M, Sato H, Matsushita S. Conformation...
Publication

Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H.: CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents. Bioorganic & Medicinal Chemistry. 21:2518-2526, 2013 .

Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H.: CD4 mimic...
Publication

Kuwata T, Takaki K, Enomoto I, Kazuhisa Y, and Matsushita S. Increased infectivity in human cells and resistance to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail. Frontiers in Microbiology/Virology. 4:1-7, 2013.

Kuwata T, Takaki K, Enomoto I, Kazuhisa Y, and Matsushita S. Increased infectivity in human cells and resistance to anti...
Publication

Nishijima T, Takano M, Ishisaka M, Komatsu H, Gatanaga H, Kikuchi Y, Endo T, Horiba M, Kaneda S, Uchiumi H, Koibuchi T, Naito T, Yoshida M, Tachikawa N, Ueda M, Yokomaku Y, Fujii T, Higasa, S., Takada, K., Yamamoto, M, Matsushita S, Tateyama M, Tanabe Y, Mitsuya H, Oka S, on behalf of the Epzicom-Truvada study team: Abacavir/Lamivudine versus Tenofovir/Emtricitabine with Atazanavir/Ritonavir for Treatment-naive Japanese Patients with HIV-1 Infection: A Randomized Multicenter Trial. Internal Medicine. 52: 735-744, 2013.

Nishijima T, Takano M, Ishisaka M, Komatsu H, Gatanaga H, Kikuchi Y, Endo T, Horiba M, Kaneda S, Uchiumi H, Koibuchi T, ...
International Conference

Matsushitas S., Yoshimura K., Maeda T., Murakami T., KD-1002 Principal Investigators and The Protocol Team of Quintiles. Passive transfer of neutralizing monoclonal antibody KD-247 reduces plasma viral load in patientschronically infected with HIV-1: a phase-1b clinical study of a humanized monoclonal antibody KD-247 (KD-1002).

Matsushita S., Yoshimura K., Maeda T., Murakami T., KD-1002 Principal Investigators and The Protocol Team of Quintiles. ...
International Conference

Matsushita S., Yoshimura K., Maeda T., Murakami T., KD-1002 Principal Investigators and The Protocol Team of Quintiles. Passive transfer of neutralizing monoclonal antibody KD-247 reduces plasma viral load in patientschronically infected with HIV-1: a phase-1b clinical study of a humanized monoclonal antibody KD-247 (KD-1002).

Matsushita S., Yoshimura K., Maeda T., Murakami T., KD-1002 Principal Investigators and The Protocol Team of Quintiles. ...
International Conference

Matsushita S. Passive transfer of neutralizing monoclonal antibody KD-247 reduces plasma viral load in patients chronically infected with HIV-1:A Phase-1b clinical study of a humanized monoclonal antibody KD-247 (KD-1002). IAS Towards an HIV Cure Symposium. 29th-30th June 2013 , Kuala Lumpur.

Matsushita S.  Passive transfer of neutralizing monoclonal antibody KD-247 reduces plasma viral load in patients chronic...
Domestic Conference

田中和樹、桑田岳夫、丸田泰広、園田貴丈、 Kristel Ramirez、松下修三.gp120のCD4-induced epitopeに結合する中和抗体の解析. 第26回日本エイズ学会学術集会・総会. 2012.11.24-11.26.(11/24発表) 横浜.

田中和樹、桑田岳夫、丸田泰広、園田貴丈、 Kristel Ramirez、松下修三.gp120のCD4-induced epitopeに結合す る中和抗体の解析.  第26回日本エイズ学会学術集会・総会. 2012.11.24-11.26....
Domestic Conference

園田貴丈、Samatchaya Boonchawalit、田中和樹、丸田泰広、Kristel Ramirez、 桑田岳夫、松下修三:CRF01_AE HIV-1 感染症例IgGの交差中和活性の解析.第26回日本エイズ学会学術集会・総会. 2012.11.24-11.26.(11/24発表) 横浜.

園田貴丈、Samatchaya Boonchawalit、田中和樹、丸田泰広、Kristel Ramirez、 桑田岳夫、松下修三: CRF01_AE HIV-1 感染症例IgGの交差中和 活性の解析. 第26回日本エイズ学会学術集会・総会...
Domestic Conference

桑田岳夫、吉村和久、松下修三:SIV感染サルから分離された中和抗体B404はV3,V4ループを含むEnv立体構造を認識する 第26回日本エイズ学会学術集会・総会. 2012.11.24-11.26.(11/24発表)横浜.

桑田岳夫、吉村和久、松下修三:SIV感染サルから分離された中和抗体B404はV3,V4ループを含むEnv立体構造を認識する 第26回日本エイズ学会学術集会・総会. 2012.11.24-11.26. 横浜.
International Conference

Sonoda T., Boonchawalit S., Gatanaga H., Tanaka K., Maruta Y., Ramirez K., Kuwata T., Matsushita S.:Cross subtype neutralizing activity of plasma antibodies from patients infected with HIV-1 CRF01_AE HIV-1. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto.

Sonoda T., Boonchawalit S., Gatanaga H., Tanaka K., Maruta Y., Ramirez K., Kuwata T., Matsushita S.:Cross subtype neutra...
International Conference

Ramirez K, Kuwata T., Maruta Y., Tanaka K., Matsushita S.: Sonoda, T, Kawanami Y, Takaki K, Enomoto I. Efficient isolation of monoclonal antibodies against HIV-1from HIV-1 infected patients. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto.

Ramirez K,  Kuwata T., Maruta Y., Tanaka K., Matsushita S.: Sonoda, T, Kawanami Y, Takaki K, Enomoto I. Efficient isolat...
International Conference

Tanaka K., Kuwata T., Maruta Y., Ramirez K., Matsushita S.: Analysis of antibodies to CD4-induced epitope on gp120. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto.

Tanaka K., Kuwata T., Maruta Y., Ramirez K., Matsushita S.: Analysis of antibodies to CD4-induced epitope on gp120. 13th...
International Conference

Maruta Y., Ramirez K., Kuwata T., Suwa Y., Morioka H., Kuwata T, Matsushita S.: Single-chain variable fragment (scFv) of anti-V3 monoclonal antibody efficiently neutralizes HIV-1 in vitro. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto.

Maruta Y., Ramirez K., Kuwata T., Suwa Y., Morioka H., Kuwata T, Matsushita S.: Single-chain variable fragment (scFv) of...
International Conference

Matsushita S., Ramirez K., Maruta Y., Harada S., Maeda T., Murakami T., Kuwata T., Yoshimura K.: CCR5-inhibitor resistance confers neutralization sensitive phenotype to primary HIV-1 isolates: Implications for the passive immunotherapy of neutralizing antibodies with CCR5 inhibitors. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto

Matsushita S., Ramirez K., Maruta Y., Harada S., Maeda T., Murakami T., Kuwata T., Yoshimura K.: CCR5-inhibitor resistan...
International Conference

Kuwata T., Takaki K., Enomoto, E., Matsushita S: Conformational epitope inbolving V3 and V4 loops is a major tartget for antibody-mediated neutralization in SIV smH635-infected macaques. 13th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2012.10.25-26, Aso, Kumamoto, Japan.

Kuwata T., Takaki K., Enomoto, E., Matsushita S: Conformational epitope inbolving V3 and V4 loops is a major tartget for...
International Conference

Maruta Y., Ramirez K., Kuwata T., Matsushita S. :Construction and characterization of neutralizing antibody fragments for efficient access to V3 epitope. AIDS Vaccine 2012, September 9-12, 2012, Boston, USA.

Maruta Y., Ramirez K., Kuwata T.,  Matsushita S. :Construction and characterization of neutralizing antibody fragments f...
International Conference

Harada S., Arai H., Narumi T., Tamamura H., Matsushita S., Yoshimura K. In vitro induction of ten CD4 mimic small compounds, NBD-556 and its analogues, resistant variants using primary R5 HIV-1. XIX International AIDS Conference (AIDS 2012), July 22-27, Washington DC, USA.

Harada S., Arai H., Narumi T., Tamamura H., Matsushita S., Yoshimura K.  In vitro induction of ten CD4 mimic small compo...
Publication

Yokoyama M, Naganawa S, Yoshimura K, Matsushita S, Sato H. Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop. PLoS ONE. 7(5): e37530, 2012.

Yokoyama M, Naganawa S, Yoshimura K, Matsushita S, Sato H. Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with...
Publication

Ong YT, Kirby KA, Hachiya A, Chiang LA, Marchand B, Yoshimura K, Murakami T, Singh K, Matsushita S, Sarafianos SG. Preparation of biological active single-chain variable antibody fragments that target the HIV-1 gp120 v3 loop. Cellular and Molecular Biology. 58: 71-79, 2012

Ong YT, Kirby KA, Hachiya A, Chiang LA, Marchand B, Yoshimura K, Murakami T, Singh K, Matsushita S, Sarafianos SG. Prepa...
International Conference

Ramirez K., Kuwata T., Yoshimura K., Kawanami Y., Enomoto I., Matsushita S. Isolation of two novel CD4-induced monoclonal antibodies (MAbs) with cross-neutralizing activity against viruses of HIV-1 B and non-B subtypes, Keystone Symposia. (Keystone, USA) Mar. 21-26, 2012.

Ramirez K., Kuwata T., Yoshimura K., Kawanami Y., Enomoto I., Matsushita S. Isolation of two novel CD4-induced monoclona...
Domestic Conference

丸田泰広、桑田岳夫、クリステル.パオラ.ラミレス.バルデス、松下修三:HIV-1のV3領域に結合する中和抗体の遺伝子組換えによる小型化の試み.第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

丸田泰広、桑田岳夫、クリステル.パオラ.ラミレス.バルデス、松下修三:HIV-1のV3領域に結合する中和抗体の遺伝子組換えによる小型化の試み.第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.
Domestic Conference

Ramirez, K, Maruta, Y., Kuwata, T., Yoshimura, K, Tamamura, H., Matsuhsita, S.:Cross-reactivity and cross-neutralizing activity of monoclonal antibody(MAbs) to CD4-induced epitope of gp120 against HIV-1B, C, CRF_01 subtype viruses. 第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

Ramirez, K., Maruta, Y., Kuwata, T., Yoshimura, K., Tamamura, H., Matsuhsita, S.:Cross-reactivity and cross-neutralizing...
Domestic Conference

桑田岳夫:SIVsmH635FC感染サルにおける特定のエピトープと遺伝子に偏った中和抗体の誘導. 第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

桑田岳夫:SIVsmH635FC感染サルにおける特定のエピトープと遺伝子に偏った中和抗体の誘導. 第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.
International Conference

Arai H., Narumi T.,Yoshimura K.,Harada S., Aikawa H., Nomura W., Matsushita S., Tamamura H. Design, synthesis and biological evaluation of CD4 mimics targeting the interaction with Asp368 and Val430 in gp120. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

Arai H., Narumi T.,Yoshimura K.,Harada S., Aikawa H., Nomura W., Matsushita S., Tamamura H. Design, synthesis and biolog...
International Conference

Narumi T., Arai H., Ochiai C.,Yoshimura K.,Harada S., Nomura W., Matsushita S., Tamamura H. SAR study of small molecular CD4 mimics targeting the dynamic supramolecular mechanism of HIV entry and their hybrid molecules with CXCR4 antagonist. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

Narumi T., Arai H., Ochiai C.,Yoshimura K.,Harada S., Nomura W., Matsushita S., Tamamura H. SAR study of small molecular...
International Conference

Harada S., Ishikawa T.,Hamji A., Matsushita S.,Yoshimura K.Impact of raltegravir pressure on the selection of HIV-1 envelope sequences in vitro. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

Harada S., Ishikawa T., Hamaji A., Matsushita S.,Yoshimura K.  Impact of raltegravir pressure on the selection of HIV-1 ...
International Conference

Yoshimura K.,Harada S.,Hamji A.,Matsushita S. Two-step escape pathway of the HIV-1 primary isolates induced by the in vitro selection of maraviroc. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

Yoshimura K., Harada S., Hamji A., Matsushita S. Two-step escape pathway of the HIV-1 primary isolates induced by the in...
International Conference

Yokoyama M., Naganawa S.,Yoshimura K., Matsushita S., Sato H. V3 region-regulated conformations of HIV-1 gp120 outer domain bring insights into structural mechanisms of immune evasion. International Union of Microbiological Societies 2011 Congress. 2011.9.6-16, Sapporo, Japan.

Yokoyama M., Naganawa S.,Yoshimura K., Matsushita S., Sato H. V3 region-regulated conformations of HIV-1 gp120 outer dom...
International Conference

Yoshimura K.,Harada S.,Hamji A., Matsushita S. Maraviroc-resistant subtype B primary HIV-1 induced in vitro selection became highly sensitive to anti-gp120 neutralizing antibodies and autologous plasma IgG under high concentrations of the CCR5 inhibitor. 6th IAS Conference on HIV Pathogenesis, Treatment and Prevention. 2011.7.17-20, Roma, Italy.

Yoshimura K.,Harada S.,Hamji A., Matsushita S. Maraviroc-resistant subtype B primary HIV-1 induced in vitro selection be...
Publication

Honda M, Ishisaka M, Ishizuka N, Kimura S, Oka S and behalf of Japanese Anti-HIV-1 QD Therapy Study Group. Open-Label Randomized Multicenter Selection Studyof Once Daily Antiretroviral Treatment Regimen Comparing Ritonavir-Boosted Atazanavir to Efavirenz with Fixed-Dose Abacavir and Lamivudine. Internal Medicine. 50: 699-705,2011.

Honda M, Ishisaka M, Ishizuka N, Kimura S, Oka S and behalf of Japanese Anti-HIV-1 QD Therapy Study Group. Open-Label Ra...
Publication

Narumi, T., Arai, H.,Yoshimura, K.,Harada, S., Nomura, W., Matsushita, S., Tamamura. H. Small molecular CD4 mimics as HIV entry inhibitors. Bioorg Med Chem , 19: 6735-6742 ,2011.

Narumi, T., Arai, H.,Yoshimura, K.,Harada, S., Nomura, W., Matsushita, S., Tamamura. H. Small molecular CD4 mimics as HI...
Domestic Conference

松下修三:共催シンポジウム2 最新の情報を明日の臨床に生かす-Year in review 2010-「病態の研究と治療薬開発の未来」. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.

松下修三:共催シンポジウム2 最新の情報を明日の臨床に生かす-Year in review 2010-「病態の研究と治療薬開発の未来」. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.
Domestic Conference

原田恵嘉、濱治有希、松下修三、吉村和久:ラルテグラビルはHIV-1 のin vitro馴化におけるEnv選択に影響する. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.

原田恵嘉、濱治有希、松下修三、吉村和久:ラルテグラビルはHIV-1 のin vitro馴化におけるEnv選択に影響する. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.
Domestic Conference

吉村和久、原田恵嘉、濱治有希、松下修三:CCR5阻害剤maraviroc(MVC)耐性誘導によるEnvの変異が中和抗体感受性に及ぼす影響. 第24回日本エイズ学会学術集会・総会.  2010.11.24 -26. 東京.

吉村和久、原田恵嘉、濱治有希、松下修三:CCR5阻害剤maraviroc(MVC)耐性誘導によるEnvの変異が中和抗体感受性に及ぼす影響. 第24回日本エイズ学会学術集会・総会.  2010.11.24 -26. 東京.
International Conference

Matsushita, S., Mouri, S., Harada, S., Yamada, Y., Tamamura, H., Yoshimura, K.: Strategy to overcome neutralization resistance of HIV-1 primary isolates. 11th GCOE Joint International Symposium Kumamoto AIDS Seminar Octoer 6-8, 2010. Kumamoto.

Matsushita, S., Mouri, S., Harada, S., Yamada, Y., Tamamura, H., Yoshimura, K.: Strategy to overcome neutralization resi...
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