Archive for 2011

  • 丸田泰広、桑田岳夫、クリステル.パオラ.ラミレス.バルデス、松下修三:HIV-1のV3領域に結合する中和抗体の遺伝子組換えによる小型化の試み.第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

     

  • Ramirez, K., Maruta, Y., Kuwata, T., Yoshimura, K., Tamamura, H., Matsuhsita, S.:Cross-reactivity and cross-neutralizing activity of monoclonal antibody(MAbs) to CD4-induced epitope of gp120 against HIV-1B, C, CRF_01 subtype viruses. 第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

     

  • 桑田岳夫:SIVsmH635FC感染サルにおける特定のエピトープと遺伝子に偏った中和抗体の誘導. 第25回日本エイズ学会学術集会・総会. 2011.11.30-12.2. 東京.

     

  • Arai H., Narumi T.,Yoshimura K.,Harada S., Aikawa H., Nomura W., Matsushita S., Tamamura H. Design, synthesis and biological evaluation of CD4 mimics targeting the interaction with Asp368 and Val430 in gp120. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

     

  • Narumi T., Arai H., Ochiai C.,Yoshimura K.,Harada S., Nomura W., Matsushita S., Tamamura H. SAR study of small molecular CD4 mimics targeting the dynamic supramolecular mechanism of HIV entry and their hybrid molecules with CXCR4 antagonist. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

     

  • Harada S., Ishikawa T., Hamaji A., Matsushita S.,Yoshimura K.  Impact of raltegravir pressure on the selection of HIV-1 envelope sequences in vitro. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

     

  • Yoshimura K., Harada S., Hamji A., Matsushita S. Two-step escape pathway of the HIV-1 primary isolates induced by the in vitro selection of maraviroc. 12th Kumamoto AIDS Seminar GCOE Joint International Symposium, 2011.10.19-21, Aso, Kumamoto, Japan.

     

  • Yokoyama M., Naganawa S.,Yoshimura K., Matsushita S., Sato H. V3 region-regulated conformations of HIV-1 gp120 outer domain bring insights into structural mechanisms of immune evasion. International Union of Microbiological Societies 2011 Congress. 2011.9.6-16, Sapporo, Japan.

     

  • Yoshimura K.,Harada S.,Hamji A., Matsushita S. Maraviroc-resistant subtype B primary HIV-1 induced in vitro selection became highly sensitive to anti-gp120 neutralizing antibodies and autologous plasma IgG under high concentrations of the CCR5 inhibitor. 6th IAS Conference on HIV Pathogenesis, Treatment and Prevention. 2011.7.17-20, Roma, Italy.

     

  • 7月1日より新メンバーをお迎えしました!!

    助教:桑田岳夫 先生
    技術補佐員:高木香織さん

    詳しくはこちら→メンバー/member

  • Honda M, Ishisaka M, Ishizuka N, Kimura S, Oka S and behalf of Japanese Anti-HIV-1 QD Therapy Study Group. Open-Label Randomized Multicenter Selection Studyof Once Daily Antiretroviral Treatment Regimen Comparing Ritonavir-Boosted Atazanavir to Efavirenz with Fixed-Dose Abacavir and Lamivudine. Internal Medicine. 50: 699-705,2011.

     

  • Narumi, T., Arai, H.,Yoshimura, K.,Harada, S., Nomura, W., Matsushita, S., Tamamura. H. Small molecular CD4 mimics as HIV entry inhibitors. Bioorg Med Chem , 19: 6735-6742 ,2011.

     

  • 22年度をもちまして、コンサルテーションプログラムを終了いたしました。これまで様々なご相談、ご意見を賜りましたことを厚くお礼申しあげます。