Archive for 2010

  • 松下修三:共催シンポジウム2 最新の情報を明日の臨床に生かす-Year in review 2010-「病態の研究と治療薬開発の未来」. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.

     

  • 原田恵嘉、濱治有希、松下修三、吉村和久:ラルテグラビルはHIV-1 のin vitro馴化におけるEnv選択に影響する. 第24回日本エイズ学会学術集会・総会. 2010.11.24 -26.東京.

     

  • 吉村和久、原田恵嘉、濱治有希、松下修三:CCR5阻害剤maraviroc(MVC)耐性誘導によるEnvの変異が中和抗体感受性に及ぼす影響. 第24回日本エイズ学会学術集会・総会.  2010.11.24 -26. 東京.

     

  • Matsushita, S., Mouri, S., Harada, S., Yamada, Y., Tamamura, H., Yoshimura, K.: Strategy to overcome neutralization resistance of HIV-1 primary isolates.  11th GCOE Joint International Symposium Kumamoto AIDS Seminar Octoer 6-8, 2010. Kumamoto.

     

  • Liu, M., Shibata, J., Harada, S., Takehisa, J., Yoshimura, K., Matsushita, S.: Impact of a point mutation V2 (L175P) in neutralization resistance mediated by functional trimer formation of Env. AIDS Vaccine 2010, Sep.28-Oct.1, 2010. Atlanta, USA.

  • Matsushita, S., Mouri, S., Harada, S., Yamada, Y., Tamamura, H., Yoshimura, K.: CD4 mimetic compound-mediated enhancement of the neutralization activities of anti-V3 and CD4i monoclonal antibodies against the standard panel of primary isolates. XVIII International AIDS Conference. July.18-23, 2010. Vienna, Austria.

  • Narumi, T., Ochiai, C., Yoshimura, K., Harada, S., Tanaka,T., Nomura,W., Arai, H., Ozaki, T., Ohashi, N., Matsushita, S., Tamamura, H. :CD4mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters. 5853- 5858, 2010.

  • Yoshimura, K., Harada, S., Shibata, J., Hatada, M., Yamada, Y., Ochiai, C., Tamamura, H., Matsushita, S. :Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds. J. Virol. 84:7558-7568, 2010.

  • Hatada, M., Yoshimura, K., Harada, S., Kawanami, Y., Shibata, J., Matsushita S. HIV-1 evasion of a neutralizing anti-V3 antibody involves acquisition of a potential glycosylation site in V2. J. Gen. Virol. 91: 1335-1345, 2010. 

  • Yamada, Y., Ochiai, C., Yoshimura, K., Tanaka, T., Ohashi, N., Narumi, T., Nomura, W., Harada, S., Matsushita, S., Tamamura, H. CD4 mimics targeting the mechanism of HIV entry. Bioorganic & Medicinal Chemistry Letters 20: 354–358, 2010.

  • Harada S., Yoshimura K., Kawanami Y., Matsushita S. In vitro selections of raltegravir resistant variants using diverse primary isolates, subtype B, C, CRF01_AE, and CRF08_BC. 2010 IYIS, 2010.3.4-5, Kumamoto, Japan.

  • Yoshimura K., Harada S., Matsushita S. Two step escape pathway of the HIV-1 subtype C primary isolate induced by the in vitro selection of Maraviroc. 17th Conference on Retroviruses and Opportunistic Infections (CROI 2010), 2010.2.16-19, San Francisco, USA.