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Publication 2002

  • Gatanaga, H., Suzuki, Y., Tsang, H., Yoshimura, K., Kavlick, M.F., Nagashima, K., Gorelick, R.J., Mardy, S., Tang, C., Summers, M.F., Mitsuya, H.: Amino acid substitutions in gag protein at non-cleavage sited are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors. J. Biol. Chem. 277:5952-5961, 2002.

  • Matsushita, S. Kimura, T. Advance in treatment strategy and immune reconstruction against HIV-1 infection. Microbiol. Immunol., 46(4):231-239, 2002.

  • Wang FX, Kimura T, Nishihara K., Yoshimura K.,Koito A, Matsushit S. Emergence of autologous neutralization-resistant variants from pre existing quasispecies during viral-rebound of human immunodeficency virus type-1 infected patients under treatment of highly active anti retroviral therapy (HAART) . J Infect Dis, 185:608-617, 2002.

  • Kimura T, Yoshimura K., Nishihara K., Maeda Y, Matsumi S,Koito A, Matsushita S. Reconstitution of spontaneous neutralizing antibody response against autologous HIV-1 in chronically infected patients during highly active antiretroviral therapy. J. Infect. Dis., 185:53-60,  2002.

  • Yoshimura K, Kato R , Kavlick MF, Nguyen A, Maroun V, Maeda K., Hussain K., Ghosh A., Erickson J, Mitsuya H. A Potent Protease Inhibitor (PI) UIC-94003 Interacting with Main Chains of HIV Protease Active Site Amino Acids and the Development of a Novel Mutation A28S in the Protease of UIC-94003-Resistant HIV. J Virol, 76:1349-1357, 2002.